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  • The relation in man between cholesterol levels in the diet and in the blood.

    Author(s) : KEYS, A.MICKELSEN, O.MILLER, E. V. O.CHAPMAN, C. B.

    Author Affiliation : Lab. Physiol. Hyg., Univ. Minnesota, Minneapolis.

    Journal article : Science (Washington) 1950 Vol.112 pp.79-81

    Abstract : Analysis of data for 312 normal menmenSubject Category: People Groups
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    on either high or low cholesterolcholesterolSubject Category: Chemicals and Chemical Groups
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    intakes (Title 3913, Vol. 19) showed that the serum cholesterol level was not significantly related to differences in habitual intake over a range of 250 to 800 mg. per day. In 41 middle-aged men who had a mean total cholesterol of 250.12 (±7.06) mg. per 100 ml. serum, the mean after one year and after at least several months on a cholesterol intake which had been reduced by 50 per cent. or more was 250-25 (± 6.68) mg. per 100 ml. serum. In a series of 4 patients the mean cholesterol value of 232.5 mg. per 100 ml. serum fell to an average of 151.8 mg. after 3 weeks on Kempner's rice-fruit diet; continuation of the diet for 2 more weeks had little further effect, but a few later observations suggested that a slow rate of decline may continue for some time. Two men with idiopathic hypercholesterolaemiahypercholesterolaemiaSubject Category: Diseases, Disorders, and Symptoms
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    hypercholesterolaemiaSubject Category: Diseases, Disorders, and Symptoms
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    , who were on a diet moderately restricted in cholesterol, were given the rice-fruit diet; during the first 2 weeks there was an average daily fall in serum cholesterol of 33 and 14 mg. When one of the 2 subjects was given a diet containing vegetable fatsfatsSubject Category: Chemicals and Chemical Groups
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    but no trace of cholesterol his blood cholesterol returned rapidly to its previous high level. After a month his diet was again modified to contain very small amounts of fat and one serving of meat or fish daily; on this diet the serum cholesterol level was stabilised for several months at 500 to 600 mg. per 100 ml.-G. F. Davison.

    ISSN : 0036-8075

    Record Number : 19501403806

    Publisher : American Association for the Advancement of Science

    Country of publication : USA

    Language of text : English

    Language of summary : English

    Indexing terms for this abstract:

    Organism descriptor(s) : manmanSubject Category: Organism Names
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    Descriptor(s) : analysisanalysisSubject Category: Techniques, Methodologies and Equipment
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    , blood analysisblood analysisSubject Category: Techniques, Methodologies and Equipment
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    , blood chemistryblood chemistrySubject Category: Miscellaneous
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    , blood serumblood serumSubject Category: Anatomical and Morphological Structures
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    , cholesterolcholesterolSubject Category: Chemicals and Chemical Groups
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    , dietsdietsSubject Category: Miscellaneous
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    , fatsfatsSubject Category: Chemicals and Chemical Groups
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    , hypercholesterolaemiahypercholesterolaemiaSubject Category: Diseases, Disorders, and Symptoms
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    , meatmeatSubject Category: Commodities and Products
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    , meat productsmeat productsSubject Category: Commodities and Products
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    , menmenSubject Category: People Groups
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    , lipid metabolism disorderslipid metabolism disordersSubject Category: Diseases, Disorders, and Symptoms
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    , blood lipidsblood lipidsSubject Category: Chemicals and Chemical Groups
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    Identifier(s) : dyslipidaemia, dyslipidemia, fat metabolism disorders, hypercholesterinemia, hypercholesterolemiahypercholesterolemiaSubject Category: Diseases, Disorders, and Symptoms
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    Broader term(s) : HomohomoSubject Category: Organism Names
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    , HominidaehominidaeSubject Category: Organism Names
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    , primatesprimatesSubject Category: Organism Names
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    , mammalsmammalsSubject Category: Organism Names
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    , vertebratesvertebratesSubject Category: Organism Names
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    , ChordatachordataSubject Category: Organism Names
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    , animalsanimalsSubject Category: Organism Names
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    , eukaryoteseukaryotesSubject Category: Organism Names
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