MOORE, F. M.; WILLIS, B. T. M.; HODGKIN, D. C.
Author Affiliation :
Chem. Crystallog. Lab., Univ. Oxford.
The mild acid hydrolysis of cyanocobalamin gives rise to a mixture of mono-and di-carboxylic acids and one tricarboxylic acid. The acid investigated forms more that 90% of the monocarboxylic acid fraction and also occurs as an intermediate in the synthesis of vitamin B12 by Propionibacterium shermanii. It can be grown in very large crystals on which the X-ray and neutron diffraction studies were made.
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Indexing terms for this abstract:
cyanocobalamin, hydrolysis, research, synthesis, vitamin B12, vitamins