Iritani, N.; Fukuda, E.; Kitamura, Y.
Author Affiliation :
Tezukayama Gakuin College, Sumiyoshi-ku, Osaka 558 Japan.
Journal of Nutrition
Three groups of male Wistar rats were maintained on 10% fat diets containing 0.5, 5 or 10% maize oil or olive oil with 80 to 400 mg DL- alpha -tocopherol 80 to 400 mg/kg. After 4 weeks on such diets, TBA (thiobarbituric acid) values in serum, liver mitochondria and microsomes, and adipose tissue increased with increasing amounts of dietary maize oil. TBA values in rats on the 10% maize oil diet were reduced with the increase of dietary tocopherol but were still higher than the corresponding values of the 10% olive oil and 0.5% maize oil groups. When the liver microsomes were incubated with Fe3+-ADP and NADPH, the relative chemiluminescence emission in the visible region with the peroxidative cleavage of endogenous lipid was higher in the 5 and 10% maize oil groups than in the 0.5% group. When oxidized maize oil was given by mouth to rats with thoracic lymph fistula, TBA-reacting substances were recovered in thoracic lymph, but iodometric peroxide was undetectable. Therefore, TBA-reacting substances in rats on the maize oil diets could have originated from the oxidative product of linoleic acid metabolism and also from the diet.
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Indexing terms for this abstract:
Organism descriptor(s) :
lipids, maize oil, peroxidation
corn oil, lipins, maize oil feeding on lipid peroxidation
Broader term(s) :
Muridae, rodents, mammals, vertebrates, Chordata, animals, eukaryotes