Author(s) :
Matthijs, M. G. R.
;
Ariaans, M. P.
;
Dwars, R. M.
;
Eck, J. H. H. van
;
Bouma, A.
;
Stegeman, A.
;
Vervelde, L.
Author Affiliation :
Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, 3508 TD Utrecht, Netherlands.
Author Email :
m.g.r.matthijs@uu.nl
Journal article
:
Veterinary Immunology and Immunopathology
2009
Vol.127
No.1/2
pp.77-84
ref.26
Abstract :
Colibacillosis results from infection with avian pathogenic
Escherichia coli bacteriabacteriaSubject Category: Organism Names
see more details. Healthy
broilersbroilersSubject Category: Organism Groups
see more details are resistant to inhaled
E. coli, but previous infection with vaccine or virulent
strainsstrainsSubject Category: Organism Groups
see more details of
Infectious Bronchitis Virusinfectious bronchitis virusSubject Category: Organism Names
see more details (IBV) predisposes
birdsbirdsSubject Category: Organism Names
see more details for severe colibacillosis. The aim of this study was to investigate how IBV affects the course of events upon infection with
E. coli. Broilers were inoculated with IBV H120 vaccine virus or virulent M41 and challenged 5 days later with
E. coli 506. A PBS and
E. coli group without previous virus
inoculationinoculationSubject Category: Techniques, Methodologies and Equipment
see more details were included. Sections of
tracheatracheaSubject Category: Anatomical and Morphological Structures
see more details, lung and airsacs were stained for CD4, CD8, γδ-TCR, αβ1-TCR, and for
macrophagesmacrophagesSubject Category: Anatomical and Morphological Structures
see more details (KUL-01) and both
pathogenspathogensSubject Category: Organism Groups
see more details. Changes in the mucociliary barrier of trachea, lung and airsacs did not predispose for bacterial superinfection. The disease in the
lungslungsSubject Category: Anatomical and Morphological Structures
see more details of the
E. coli group and both IBV/
E. coli groups was similar.
LesionslesionsSubject Category: Diseases, Disorders, and Symptoms
see more details in the airsacs were more pronounced and of longer duration in the IBV/
E. coli groups. The immunocytological changes differed substantially between the
E. coli group and both IBV/
E. coli groups. In trachea, lungs and airsacs the CD4+ and CD8+ populations were significantly larger than in the
E. coli and PBS groups. In the lungs and the airsacs the macrophages were more numerous in the IBV/
E. coli and the
E. coli groups than in the PBS group. The presence of high numbers of T cells and macrophages in IBV infected birds most likely induced an altered
immune responseimmune responseSubject Category: Natural Processes
see more details, which is responsible for the enhanced clinical signs of colibacillosis.
ISSN :
0165-2427
DOI :
10.1016/j.vetimm.2008.09.016
URL :
http://www.sciencedirect.com/science/...
Record Number :
20093101458
Publisher :
Elsevier
Location of publication :
Amsterdam
Country of publication :
Netherlands
Language of text :
English
Indexing terms for this abstract:
Organism descriptor(s) :
BacteriabacteriaSubject Category: Organism Names
see more details, birdsbirdsSubject Category: Organism Names
see more details, EscherichiaescherichiaSubject Category: Organism Names
see more details, Escherichia coliescherichia coliSubject Category: Organism Names
see more details, fowlsfowlsSubject Category: Organism Names
see more details, infectious bronchitis virusinfectious bronchitis virusSubject Category: Organism Names
see more details, virusesvirusesSubject Category: Organism Names
see more details
Descriptor(s) :
avian infectious bronchitisavian infectious bronchitisSubject Category: Diseases, Disorders, and Symptoms
see more details, bacterial diseasesbacterial diseasesSubject Category: Diseases, Disorders, and Symptoms
see more details, broilersbroilersSubject Category: Organism Groups
see more details, bronchitisbronchitisSubject Category: Diseases, Disorders, and Symptoms
see more details, CD4 antigenscd4 antigensSubject Category: Chemicals and Chemical Groups
see more details, CD8 antigenscd8 antigensSubject Category: Chemicals and Chemical Groups
see more details, Escherichia coli infectionsescherichia coli infectionsSubject Category: Diseases, Disorders, and Symptoms
see more details, Escherichia infectionsescherichia infectionsSubject Category: Diseases, Disorders, and Symptoms
see more details, immune responseimmune responseSubject Category: Natural Processes
see more details, immunizationimmunizationSubject Category: Techniques, Methodologies and Equipment
see more details, immunologyimmunologySubject Category: Disciplines, Occupations and Industries
see more details, infectionsinfectionsSubject Category: Diseases, Disorders, and Symptoms
see more details, infectious diseasesinfectious diseasesSubject Category: Diseases, Disorders, and Symptoms
see more details, inhalationinhalationSubject Category: Miscellaneous
see more details, inoculationinoculationSubject Category: Techniques, Methodologies and Equipment
see more details, lesionslesionsSubject Category: Diseases, Disorders, and Symptoms
see more details, lungslungsSubject Category: Anatomical and Morphological Structures
see more details, macrophagesmacrophagesSubject Category: Anatomical and Morphological Structures
see more details, pathogenspathogensSubject Category: Organism Groups
see more details, poultrypoultrySubject Category: Organism Groups
see more details, respiratory systemrespiratory systemSubject Category: Anatomical and Morphological Structures
see more details, strainsstrainsSubject Category: Organism Groups
see more details, T lymphocytest lymphocytesSubject Category: Anatomical and Morphological Structures
see more details, tracheatracheaSubject Category: Anatomical and Morphological Structures
see more details, vaccinesvaccinesSubject Category: Commodities and Products
see more details, viral diseasesviral diseasesSubject Category: Diseases, Disorders, and Symptoms
see more details, virulencevirulenceSubject Category: Miscellaneous
see more details, respiratory diseasesrespiratory diseasesSubject Category: Diseases, Disorders, and Symptoms
see more details
Identifier(s) :
bacterial infections, bacterioses, bacterium, CD4, CD8, chickens, colibacteriosis, communicable diseases, domesticated birds, E. coli, IBV infection, immune sensitization, immunity reactions, immunological reactions, superinfections, T cells, viral infections
Broader term(s) :
prokaryotesprokaryotesSubject Category: Organism Names
see more details, vertebratesvertebratesSubject Category: Organism Names
see more details, ChordatachordataSubject Category: Organism Names
see more details, animalsanimalsSubject Category: Organism Names
see more details, eukaryoteseukaryotesSubject Category: Organism Names
see more details, EnterobacteriaceaeenterobacteriaceaeSubject Category: Organism Names
see more details, EnterobacterialesenterobacterialesSubject Category: Organism Names
see more details, GammaproteobacteriagammaproteobacteriaSubject Category: Organism Names
see more details, ProteobacteriaproteobacteriaSubject Category: Organism Names
see more details, BacteriabacteriaSubject Category: Organism Names
see more details, EscherichiaescherichiaSubject Category: Organism Names
see more details, Gallus gallusgallus gallusSubject Category: Organism Names
see more details, GallusgallusSubject Category: Organism Names
see more details, PhasianidaephasianidaeSubject Category: Organism Names
see more details, GalliformesgalliformesSubject Category: Organism Names
see more details, birdsbirdsSubject Category: Organism Names
see more details, Avian coronavirusavian coronavirusSubject Category: Organism Names
see more details, GammacoronavirusgammacoronavirusSubject Category: Organism Names
see more details, CoronavirinaecoronavirinaeSubject Category: Organism Names
see more details, CoronaviridaecoronaviridaeSubject Category: Organism Names
see more details, NidoviralesnidoviralesSubject Category: Organism Names
see more details, positive-sense ssRNA Virusespositive-sense ssrna virusesSubject Category: Organism Names
see more details, ssRNA Virusesssrna virusesSubject Category: Organism Names
see more details, RNA Virusesrna virusesSubject Category: Organism Names
see more details, virusesvirusesSubject Category: Organism Names
see more details