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  • Effects of maternal stress during pregnancy on offspring before and after birth: mechanism of action from a hypothalamus-pituitary-adrenocortical axis.

    Author(s) : Li LiuanWu ZhanWangZhao RuQian

    Author Affiliation : Key Laboratory of Animal Physiology and Biochemistry, Nanjing Agricultural University, Nanjing 210095, China.

    Author Email : anliuli2003@163.comlapb@njau.edu.cn

    Journal article : Chinese Journal of Animal Nutrition 2010 Vol.22 No.5 pp.1138-1141 ref.18

    Abstract : Normal hypothalamushypothalamusSubject Category: Anatomical and Morphological Structures
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    -pituitarypituitarySubject Category: Anatomical and Morphological Structures
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    -adrenocortical (HPA) axis activity is essential for animal physical health. Maternal stress during pregnancypregnancySubject Category: Miscellaneous
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    programs HPA axis function, as well as the growth and development of offspring before and after birth. Fetal HPA axis is the most susceptible system responding to maternal stress. These impacts are achieved by alterations in glucocorticoid receptor and mineralocorticoid receptor expressions in hippocampus, hypothalamus and pituitary of the offspring. Adrenal cortexadrenal cortexSubject Category: Anatomical and Morphological Structures
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    as an important component of HPA axis may also be a target of maternal programming, which awaits further investigation.

    ISSN : 1006-267X

    URL : http://www.chinajan.com/

    Record Number : 20103318727

    Publisher : Chinese Association of Animal Science and Veterinary Medicine

    Location of publication : Beijing

    Country of publication : China

    Language of text : Chinese

    Language of summary : English

    Indexing terms for this abstract:

    Descriptor(s) : adrenal cortexadrenal cortexSubject Category: Anatomical and Morphological Structures
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    , domestic animalsdomestic animalsSubject Category: Organism Groups
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    , embryonic developmentembryonic developmentSubject Category: Natural Processes
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    , fetal developmentfetal developmentSubject Category: Miscellaneous
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    , glucocorticoidsglucocorticoidsSubject Category: Chemicals and Chemical Groups
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    , hormonal controlhormonal controlSubject Category: Miscellaneous
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    , hormone secretionhormone secretionSubject Category: Natural Processes
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    , hypothalamushypothalamusSubject Category: Anatomical and Morphological Structures
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    , livestocklivestockSubject Category: Organism Groups
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    , mineralocorticoidsmineralocorticoidsSubject Category: Chemicals and Chemical Groups
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    , parturitionparturitionSubject Category: Miscellaneous
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    , pituitarypituitarySubject Category: Anatomical and Morphological Structures
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    , pregnancypregnancySubject Category: Miscellaneous
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    , reproductionreproductionSubject Category: Miscellaneous
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    , stressstressSubject Category: Miscellaneous
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    , stress responsestress responseSubject Category: Miscellaneous
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    Identifier(s) : embryo development, embryo growth, endocrine control, endocrine secretion, gestation, hormonal regulation, hypophysis, pituitary gland