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  • The efficacy of macrocyclic lactones and benzimidazoles combination in equine strongylidosis.

    Author(s) : Cernea, L. C.Cernea, M.Ognean, L.Năstasa, V.Răileanu, Ș.Mareș, M.Chereji, A.Carvalho, L. M. M. de

    Author Affiliation : USAMV Cluj-Napoca, Calea Mănăștur, No. 3-5, 400372, Cluj-Napoca, Romania.

    Author Email : mscernea@yahoo.com

    Journal article; Conference paper : Lucrări Științifice - Medicină Veterinară, Universitatea de Științe Agricole și Medicină Veterinară "Ion Ionescu de la Brad" Iași 2010 Vol.53 No.12(3) pp.562-565 ref.6

    Conference Title : Progress and perspectives in veterinary medicine, Iași, Romania, 10-11 June, 2010.

    Abstract : In vitro research conducted on a number of 30 horseshorsesSubject Category: Organism Names
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    from CSV Abrud has the purpose of testing the combination of IvermectinivermectinSubject Category: Chemicals and Chemical Groups
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    , FenbendazolefenbendazoleSubject Category: Chemicals and Chemical Groups
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    , AlbendazolealbendazoleSubject Category: Chemicals and Chemical Groups
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    , MebendazolemebendazoleSubject Category: Chemicals and Chemical Groups
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    combination, on strongyls from horses. Using in larvae development assay Ivermectin and Mebendazole reveal that these combination is more effective than the results obtained in separate testing of the two substances, thanks to the different mechanism of action of the two substances. Calculation of Y parameter (prediction equation) leads to a maximum value of -1609.64. The combination of Ivermectin and Fenbendazole, show that the risk of induction of adaptive phenomena on strongyls is much higher. The combination of Ivermectin and Albendazole highlighted a lethal concentration 50 (LC50) with the value of -0.0696 mg/ml which is higher than the values obtained by separate testing of each molecules.

    ISSN : 1454-7406

    URL : http://www.univagro-iasi.ro/.../

    Record Number : 20103374923

    Publisher : Universitatea de Științe Agricole și Medicină Veterinară"Ion Ionescu de la Brad" Iași

    Location of publication : Iași

    Country of publication : Romania

    Language of text : English

    Indexing terms for this abstract:

    Organism descriptor(s) : EquusequusSubject Category: Organism Names
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    , horseshorsesSubject Category: Organism Names
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    , NematodanematodaSubject Category: Organism Names
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    , StrongylidaestrongylidaeSubject Category: Organism Names
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    Descriptor(s) : albendazolealbendazoleSubject Category: Chemicals and Chemical Groups
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    , animal parasitic nematodesanimal parasitic nematodesSubject Category: Organism Groups
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    , benzimidazolebenzimidazoleSubject Category: Chemicals and Chemical Groups
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    , benzimidazolesbenzimidazolesSubject Category: Chemicals and Chemical Groups
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    , drug combinationsdrug combinationsSubject Category: Miscellaneous
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    , fenbendazolefenbendazoleSubject Category: Chemicals and Chemical Groups
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    , helminthoseshelminthosesSubject Category: Diseases, Disorders, and Symptoms
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    , helminthshelminthsSubject Category: Organism Groups
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    , infectionsinfectionsSubject Category: Diseases, Disorders, and Symptoms
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    , ivermectinivermectinSubject Category: Chemicals and Chemical Groups
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    , lactoneslactonesSubject Category: Chemicals and Chemical Groups
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    , mebendazolemebendazoleSubject Category: Chemicals and Chemical Groups
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    , nematode infectionsnematode infectionsSubject Category: Diseases, Disorders, and Symptoms
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    , parasitesparasitesSubject Category: Organism Groups
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    , parasitosesparasitosesSubject Category: Diseases, Disorders, and Symptoms
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    , potencypotencySubject Category: Properties
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    Identifier(s) : animal-parasitic nematodes, nematode parasites of animals, nematodes, nematodes of animals, parasitic diseases, parasitic infestations, parasitic worms, parasitosis, Secernentea, Strongylida

    Broader term(s) : EquusequusSubject Category: Organism Names
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    , EquidaeequidaeSubject Category: Organism Names
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    , PerissodactylaperissodactylaSubject Category: Organism Names
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    , mammalsmammalsSubject Category: Organism Names
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    , vertebratesvertebratesSubject Category: Organism Names
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    , ChordatachordataSubject Category: Organism Names
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    , animalsanimalsSubject Category: Organism Names
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    , eukaryoteseukaryotesSubject Category: Organism Names
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    , invertebratesinvertebratesSubject Category: Organism Names
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    , RhabditidarhabditidaSubject Category: Organism Names
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    , ChromadoriachromadoriaSubject Category: Organism Names
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    , ChromadoreachromadoreaSubject Category: Organism Names
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    , NematodanematodaSubject Category: Organism Names
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