You are signed in as:
  • IFPRI
  • Signed in via:
  • IP Address

  • Choose a colour
  • Quantitative comparison of iodothyronine deiodinase I and II mRNA expression in ovine tissues.

    Author(s) : Foroughi, M. A.Dehghani, H.

    Author Affiliation : Department of Basic Science, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad 91779-48974, Iran.

    Author Email : mohamadj_foroughi@yahoo.comdehghani@um.ac.ir

    Journal article : Research in Veterinary Science 2013 Vol.95 No.3 pp.891-893 ref.26

    Abstract : Iodothyronine deiodinases I and II (DIO1 and DIO2) remove iodineiodineSubject Category: Chemicals and Chemical Groups
    see more details
    from T4 to convert it to a more biologically active T3. The relative contribution of different tissue deiodinases to the establishment of a euthyroid state in sheepsheepSubject Category: Organism Names
    see more details
    is not known. The objective of this study was to quantitate the amounts of transcriptiontranscriptionSubject Category: Natural Processes
    see more details
    of DIO1 and DIO2 deiodinases in different ovine tissues. Using RT-qPCR, we found that DIO1 deiodinase is transcribed in skeletal muscleskeletal muscleSubject Category: Anatomical and Morphological Structures
    see more details
    , kidney, and heartheartSubject Category: Anatomical and Morphological Structures
    see more details
    , more than thyroid, in diaphragmdiaphragmSubject Category: Anatomical and Morphological Structures
    see more details
    in quantities very similar to thyroid, and in liverliverSubject Category: Anatomical and Morphological Structures
    see more details
    , spleenspleenSubject Category: Anatomical and Morphological Structures
    see more details
    , lung, and mammary gland lower than thyroid. We also found that the level of DIO2 transcription in all other tissues was lower than that in thyroid. In clinical settings, measurement of DIO1 and DIO2 expression in a given tissue may provide important clues on the intensity of seleniumseleniumSubject Category: Chemicals and Chemical Groups
    see more details
    deficiencydeficiencySubject Category: Diseases, Disorders, and Symptoms
    see more details
    and its effectseffectsSubject Category: Properties
    see more details
    on the metabolismmetabolismSubject Category: Natural Processes
    see more details
    of thyroid hormonesthyroid hormonesSubject Category: Chemicals and Chemical Groups
    see more details
    .

    ISSN : 0034-5288

    DOI : 10.1016/j.rvsc.2013.07.010

    Record Number : 20143017932

    Publisher : Elsevier Ltd

    Location of publication : Oxford

    Country of publication : UK

    Language of text : English

    Indexing terms for this abstract:

    Organism descriptor(s) : sheepsheepSubject Category: Organism Names
    see more details

    Descriptor(s) : deficiencydeficiencySubject Category: Diseases, Disorders, and Symptoms
    see more details
    , diaphragmdiaphragmSubject Category: Anatomical and Morphological Structures
    see more details
    , effectseffectsSubject Category: Properties
    see more details
    , gene expressiongene expressionSubject Category: Miscellaneous
    see more details
    , heartheartSubject Category: Anatomical and Morphological Structures
    see more details
    , hormoneshormonesSubject Category: Chemicals and Chemical Groups
    see more details
    , iodineiodineSubject Category: Chemicals and Chemical Groups
    see more details
    , liverliverSubject Category: Anatomical and Morphological Structures
    see more details
    , lungslungsSubject Category: Anatomical and Morphological Structures
    see more details
    , mammary glandsmammary glandsSubject Category: Anatomical and Morphological Structures
    see more details
    , messenger RNAmessenger rnaSubject Category: Chemicals and Chemical Groups
    see more details
    , metabolismmetabolismSubject Category: Natural Processes
    see more details
    , mineral deficienciesmineral deficienciesSubject Category: Diseases, Disorders, and Symptoms
    see more details
    , molecular geneticsmolecular geneticsSubject Category: Miscellaneous
    see more details
    , musclesmusclesSubject Category: Anatomical and Morphological Structures
    see more details
    , seleniumseleniumSubject Category: Chemicals and Chemical Groups
    see more details
    , skeletal muscleskeletal muscleSubject Category: Anatomical and Morphological Structures
    see more details
    , skeletonskeletonSubject Category: Anatomical and Morphological Structures
    see more details
    , spleenspleenSubject Category: Anatomical and Morphological Structures
    see more details
    , thyroid glandthyroid glandSubject Category: Anatomical and Morphological Structures
    see more details
    , thyroid hormonesthyroid hormonesSubject Category: Chemicals and Chemical Groups
    see more details
    , transcriptiontranscriptionSubject Category: Natural Processes
    see more details
    , veterinary scienceveterinary scienceSubject Category: Disciplines, Occupations and Industries
    see more details

    Identifier(s) : biochemical genetics, DNA transcription, mRNA, thyroid

    Broader term(s) : OvisovisSubject Category: Organism Names
    see more details
    , BovidaebovidaeSubject Category: Organism Names
    see more details
    , ruminantsruminantsSubject Category: Organism Names
    see more details
    , ArtiodactylaartiodactylaSubject Category: Organism Names
    see more details
    , mammalsmammalsSubject Category: Organism Names
    see more details
    , vertebratesvertebratesSubject Category: Organism Names
    see more details
    , ChordatachordataSubject Category: Organism Names
    see more details
    , animalsanimalsSubject Category: Organism Names
    see more details
    , eukaryoteseukaryotesSubject Category: Organism Names
    see more details