Author(s) :
Wang Yao
;
Teng MiaoMiao
;
Wang DeZhen
;
Yan Jin
;
Miao JiYan
;
Zhou ZhiQiang
;
Zhu WenTao
Author Affiliation :
Beijing Advanced Innovation Center for Food Nutrition and Human Health, Department of Applied Chemistry, China Agricultural University, Beijing 100193, China.
Author Email :
wentaozhu@cau.edu.cn
Journal article
:
Environmental Pollution
2017
Vol.229
pp.264-271
Abstract :
Although
epoxiconazoleepoxiconazoleSubject Category: Chemicals and Chemical Groups
see more details is the worldwidely used fungicide, limited information is known about its toxic
effectseffectsSubject Category: Properties
see more details and
bioaccumulationbioaccumulationSubject Category: Miscellaneous
see more details behavior in freshwater
ecosystemsecosystemsSubject Category: Habitats
see more details. In this study, zebrafish were exposed to epoxiconazole at concentrations of 100 and 1000 µg L
- for 21 d.
1H NMR-based
metabolomicsmetabolomicsSubject Category: Miscellaneous
see more details analysis showed that low- and high-dose epoxiconazole exposure resulted in two similar but not identical patterns for the change of endogenous
metabolitesmetabolitesSubject Category: Chemicals and Chemical Groups
see more details related to energy, lipid and amino acid metabolism. The expression of
genesgenesSubject Category: Miscellaneous
see more details associated with mitochondrial respiratory chain,
ATPatpSubject Category: Chemicals and Chemical Groups
see more details synthesis and fatty acid β-oxidation were further measured to explore the reason for the disturbed
energy metabolismenergy metabolismSubject Category: Natural Processes
see more details, finding epoxiconazole had an
inhibitioninhibitionSubject Category: Miscellaneous
see more details effect on the genes expression of the above ways. Significant enantioselectivity was observed with (+)-epoxiconazole enrichment in the bioaccumulation process. These results will be of great importance in understanding the toxic effects induced by epoxiconazole and provide important basis for its comprehensive
environmental assessmentenvironmental assessmentSubject Category: Techniques, Methodologies and Equipment
see more details.
ISSN :
0269-7491
DOI :
10.1016/j.envpol.2017.05.087
Record Number :
20173349886
Publisher :
Elsevier Ltd
Location of publication :
Oxford
Country of publication :
UK
Language of text :
English
Indexing terms for this abstract:
Organism descriptor(s) :
DaniodanioSubject Category: Organism Names
see more details, Danio reriodanio rerioSubject Category: Organism Names
see more details
Descriptor(s) :
aquatic animalsaquatic animalsSubject Category: Organism Groups
see more details, aquatic environmentaquatic environmentSubject Category: Habitats
see more details, aquatic organismsaquatic organismsSubject Category: Organism Groups
see more details, ATPatpSubject Category: Chemicals and Chemical Groups
see more details, bioaccumulationbioaccumulationSubject Category: Miscellaneous
see more details, ecosystemsecosystemsSubject Category: Habitats
see more details, effectseffectsSubject Category: Properties
see more details, energy metabolismenergy metabolismSubject Category: Natural Processes
see more details, environmental assessmentenvironmental assessmentSubject Category: Techniques, Methodologies and Equipment
see more details, epoxiconazoleepoxiconazoleSubject Category: Chemicals and Chemical Groups
see more details, fatty acidsfatty acidsSubject Category: Chemicals and Chemical Groups
see more details, fresh waterfresh waterSubject Category: Miscellaneous
see more details, freshwater ecologyfreshwater ecologySubject Category: Miscellaneous
see more details, functional genomicsfunctional genomicsSubject Category: Miscellaneous
see more details, fungicidesfungicidesSubject Category: Chemicals and Chemical Groups
see more details, gene expressiongene expressionSubject Category: Miscellaneous
see more details, genesgenesSubject Category: Miscellaneous
see more details, inhibitioninhibitionSubject Category: Miscellaneous
see more details, metabolismmetabolismSubject Category: Natural Processes
see more details, metabolitesmetabolitesSubject Category: Chemicals and Chemical Groups
see more details, metabolomicsmetabolomicsSubject Category: Miscellaneous
see more details, mitochondriamitochondriaSubject Category: Anatomical and Morphological Structures
see more details, pesticidespesticidesSubject Category: Chemicals and Chemical Groups
see more details, pollutionpollutionSubject Category: Miscellaneous
see more details, toxicitytoxicitySubject Category: Properties
see more details
Identifier(s) :
adenosine triphosphate, aquatic species, environmental pollution, freshwater biology, fungistats
Broader term(s) :
CyprinidaecyprinidaeSubject Category: Organism Names
see more details, CypriniformescypriniformesSubject Category: Organism Names
see more details, OsteichthyesosteichthyesSubject Category: Organism Names
see more details, fishesfishesSubject Category: Organism Names
see more details, vertebratesvertebratesSubject Category: Organism Names
see more details, ChordatachordataSubject Category: Organism Names
see more details, animalsanimalsSubject Category: Organism Names
see more details, eukaryoteseukaryotesSubject Category: Organism Names
see more details, DaniodanioSubject Category: Organism Names
see more details